Research Article
Enrichment, Development, and Assessment of Indian Basil Oil Based Antiseptic Cream Formulation Utilizing Hydrophilic-Lipophilic Balance Approach
Table 2
Basil oil cream formulation.
| | Formulations/ingredients (%) | CR1 | CR2 | CR3 | CR4 | CR5 | CR6 | CR7 | CR8 |
| | Light liquid paraffin | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | 6.00 | | White petroleum jelly | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | | Basil oil | 4.00 | 4.00 | 4.00 | 4.00 | 4.00 | 4.00 | 4.00 | 4.00 | | Paraffin wax | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | 2.00 | | Cetyl alcohol | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | | Stearyl alcohol | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 | | Water | q.s. | q.s. | q.s. | q.s. | q.s. | q.s. | q.s. | q.s. |
| | | Emulsifier blend 1 | Emulsifier blend 2 | | | 2% | 4% | 6% | 8% | 2% | 4% | 6% | 8% |
| | Tween 80 | 1.55 | 3.10 | 4.65 | 6.20 | — | — | — | — | | GMS | 0.45 | 0.90 | 1.35 | 1.80 | 1.58 | 3.15 | 4.72 | 6.30 | | SLS | — | — | — | — | 0.42 | 0.85 | 1.28 | 1.70 |
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HLB of cream formulation is 12.87 (calculated).
Emulsifier blend 1: GMS : Tween 80—1 : 3.45.
Emulsifier blend 2: GMS : SLS—3.68 : 1.
GMS: glycerol monostearate; SLS: sodium lauryl sulfate; q.s.: quantity sufficient; CR: cream formulation.
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