Estimation of Ion Competition via Correlated Responsivity Offset in Linear Ion Trap Mass Spectrometry Analysis: Theory and Practical Use in the Analysis of Cyanobacterial Hepatotoxin Microcystin-LR in Extracts of Food Additives
Calibration curves for MCYST-LR in three different matrices (MeOH, Stigeoclonium sp. extract, and salmon hydrolyzate) and the computed limit of detection (LOD) for a protonated MCYST-LR molecular ion mass of 995. From (a) to (c) the calibration curve of MCYST-LR in MeOH, the calibration curve of MCYST-LR in Stigeoclonium sp.extract, and the calibration curve of MCYST-LR in salmon hydrolyzate. The blue stars are the maximal intensities evaluated by DataAnalysis, the green triangles are the maximal intensities evaluated by EMP (Expertomica metabolite profiling), and the red line is the computed LOD in a given matrix. The calibration curve trend continues below the LOD value. Units for graph axes are follows: μg/mL for the -axis and counts for the -axis.