Review Article

Human Induced Pluripotent Stem Cells from Basic Research to Potential Clinical Applications in Cancer

Table 1

Advantages and disadvantages in iPSCs utilization.

AdvantagesDisadvantages

Avoid human embryos’ useOncogene use for induction iPSCs phenotype
Capacity to induce stem cell like phenotypeUse of integrative DNA methodology
New promises to cellular therapyGenomic instability and aberrations
Possibility of studying several diseases, including cancerIncrease risk of the development of cancer