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BioMed Research International
Volume 2013 (2013), Article ID 435387, 4 pages
Clinical Study

Inhalation Anesthesia with Sevoflurane during Intravitreal Bevacizumab Injection in Infants with Retinopathy of Prematurity

1Department of Anesthesiology, Faculty of Medicine, Dicle University, 21280 Diyarbakır, Turkey
2Department of Ophthalmology, Faculty of Medicine, Dicle University, 21280 Diyarbakır, Turkey

Received 4 April 2013; Accepted 26 May 2013

Academic Editor: Tatsushi Mutoh

Copyright © 2013 Orhan Tokgöz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Bacground. To investigate the anesthetic management in premature infants with retinopathy of prematurity (ROP) treated with intravitreal bevacizumab (IVB) injections. Methods. A retrospective chart review was performed for the patients with ROP who had IVB injection. Clinical characteristics, demographic variables, anesthetic medications, operation techniques, time intervals, and complications were recorded. Results. Sixty-six eyes of 33 patients (23 males, 10 females) with type 1 ROP who were treated with IVB were included. A total of 66 anesthetic applications were performed. Mean gestational age at birth was 28.3 weeks (range 25–33). Mean birth weight was 1300 g (range 600–1850). Serious ocular and systemic complications were not observed in any infant. Conclusion. Inhalation anesthesia with sevoflurane during IVB treatment in premature infants with ROP may be appropriate for anesthetic management.