Research Article

Chromogenic In Situ Hybridization and p16/Ki67 Dual Staining on Formalin-Fixed Paraffin-Embedded Cervical Specimens: Correlation with HPV-DNA Test, E6/E7 mRNA Test, and Potential Clinical Applications

Figure 2

Correlation between CISH results and histological diagnosis ( ). P: punctate pattern; D/P: diffuse and punctated (mixed) pattern; D: diffuse pattern. CIN2+: Cervical intraepithelial neoplasia grade 2 or greater (including CIN2, CIN3, and invasive squamous cell carcinoma); CIN2−: less than Cervical Intraepithelial Neoplasia grade 2 (including CIN1 and negative for dysplasia.
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