Chromogenic In Situ Hybridization and p16/Ki67 Dual Staining on Formalin-Fixed Paraffin-Embedded Cervical Specimens: Correlation with HPV-DNA Test, E6/E7 mRNA Test, and Potential Clinical Applications

Table 5

Correlation between p16 and p16/Ki67 immunohistochemistry and E6/E7 mRNA test.

Immunohistochemistry	E6/E7 mRNA test
	Positive (%)	Negative (%)	Total
p16 positive	35 (77.8)	2 (11.1)	37 (58.7)
p16 negative	10 (22.2)	16 (88.9)	26 (41.3)
Total	45	18	63
p16/Ki67 dual stain positive	40 (88.9)	2 (11.1)	42 (66.7)
p16/Ki67 dual stain negative	5 (11.1)	16 (88.8)	21 (33.3)
Total	45	18	63