Role of Toll-Interacting Protein Gene Polymorphisms in Leprosy Mexican Patients

Table 3

Haplotype frequencies of the rs3750920, rs5744015, and rs3750919 TOLLIP polymorphisms in LL and HS.

Haplotype	LL (2𝑛=196); n (%)	HS (2𝑛=304); n (%)	OR; CI (95%)	𝑃 value
CCG	96 (48.9)	160 (52.7)	*
CCA	15 (7.68)	32 (10.5)	0.78 (0.40–1.52)	𝑃=0.47
CAA	0 (0)	1 (0.002)	0.55 (0.02–13.7)	𝑃=0.72
CAG	0 (0)	2 (0.008)	0.33 (0.02–7.00)	𝑃=0.48
TCG	38 (19.4)	61 (20.2)	1.03 (0.64–1.67)	𝑃=0.88
TCA	45 (22.9)	47 (15.4)	1.59 (0.99–2.58)	𝑃=0.06
TAA	0 (0)	1 (0.002)	1.66 (0.03–84.5)	𝑃=0.80
TAG	2 (1.02)	0 (0)	8.3 (0.40–175)	𝑃=0.17

LL: lepromatous leprosy; HS: healthy subjects; OR: odds ratio; CI: confidence interval; *Reference haplotype.