Figure 1: Synthetic scheme of FPAMT. The KF and kryptofix complex were incubated with N-t-butoxycarbonyl-O-[3-tosylpropyl]-α-methyl tyrosine ethyl ester (compound 1) in acetonitrile for synthesis of N-t-butoxycarbonyl-O-[3-19F-fluoropropyl]-α-methyl tyrosine ethyl ester (compound 2). After deprotection of butoxycarbonyl (BOC) of compound 2, O-[3-19F-fluoropropyl]-α-methyl tyrosine ethyl ester (compound 3) was synthesized. The final step is to yield FPAMT (compound 4) by deesterification of compound 3.