Synthesis and Biological Evaluation of O-[3-¹⁸F-fluoropropyl]-α-methyl Tyrosine in Mesothelioma-Bearing Rodents

Figure 4

μPET images of ¹⁸F-FPAMT and ¹⁸F-FDG in mesothelioma-bearing rats (lower body: IL-45, at 45 min). The SUV ratios of tumor to muscle for ¹⁸F-FPAMT and ¹⁸F-FDG were 2.82 and 8.26, respectively. Computer-outlined regions of interest (ROI) (counts per pixel) for tumor and muscle at the corresponding time interval were used to generate a dynamic plot. Dynamic plot was from 0 to 45 minutes.