Research Article

Reevaluating the Role of Acanthamoeba Proteases in Tissue Invasion: Observation of Cytopathogenic Mechanisms on MDCK Cell Monolayers and Hamster Corneal Cells

Table 1

Summary of pathogenicity tests of A. castellanii and A. polyphaga in a murine model according to Culbertson et al. [19].

% VirulenceAmoebae recoveryDead postinoculation

A. castellanii 60%Brain, lung, kidney, liver5–9 days
A. polyphaga 20%Brain, lung7–20 days