Figure 3: Time course of lactate (a) and glucose (b) production from alanine in the perfused liver from rats of four experimental groups. Livers from fasted rats were perfused as described in Section 2. Alanine was infused during 30 minutes (10 to 40 minutes perfusion time). Samples of the effluent perfusion fluid were collected for the enzymatic metabolite assay. Group I, control; group II, A. blazei pretreatment; group III, paracetamol injury; group IV, A. blazei pretreatment + paracetamol injury.