Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography

Table 3

Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of calcium scoring in assessing coronary artery disease under patient-based (PB) and vessel-based (VB) analyses.

Calcium scoring	0		1–10		11–100		101–400		401–1000		≧1001
	PB	VB	PB	VB	PB	VB	PB	VB	PB	VB	PB	VB
Sensitivity	100%	100%	Nil	91.6%	95.8%	86.3%	81.7%	61.1%	56.3%	33.6%	39.4%	11.5%
Specificity	0%	0%	Nil	46.1%	41.4%	53.2%	62.1%	77.3%	86.2%	91.8%	100%	98.9%
PPV	32.8%	71%	Nil	45.3%	80%	47.3%	84.1%	56.7%	90.9%	66.7%	100%	83.3%
NPV	Nil	Nil	Nil	91.9%	80%	88.8%	58.1%	80.3%	44.6%	74%	40.3%	69.6%
Accuracy	32.8%	71%	Nil	61%	80%	64%	76%	72%	65%	72.8%	57%	70.3%

Nil: no patients in respective group.