Characterization of Antibiotic-Loaded Alginate-Osa Starch Microbeads Produced by Ionotropic Pregelation

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2">Sample</td><td align="center" colspan="3">Temperature (°C)</td><td align="center" rowspan="2"><svg height="11.425" id="M50" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 25.924999 11.425" width="25.924999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> (J/g)</td><td align="center" rowspan="2"><span style="width: 18.8375px;"><svg height="18.799999" id="M51" style="vertical-align:-5.76988pt" version="1.1" viewbox="0 0 18.8375 18.799999" width="18.8375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td></tr><tr class="thead"><td align="center">Onset</td><td align="center">Peak</td><td align="center">Endset</td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td align="left" rowspan="2">Alginate</td><td align="center">161.40</td><td align="center">163.26</td><td align="center">170.33</td><td align="center">332.98 </td><td align="center">52.10</td></tr><tr><td align="center">209.59</td><td align="center">237.36</td><td align="center">263.35</td><td align="center"><span style="width: 54.775002px;"><svg height="11.175" id="M52" style="vertical-align:-0.20474pt" version="1.1" viewbox="0 0 54.775002 11.175" width="54.775002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center"> </td></tr><tr><td align="left">OSA starch</td><td align="center">182.65</td><td align="center">184.31</td><td align="center">189.55</td><td align="center">125.03 </td><td align="center">67.06</td></tr><tr><td align="left">Unloaded alginate/OSA starch beads</td><td align="center">145.57</td><td align="center">196.08</td><td align="center">220.65</td><td align="center">661.07 </td><td align="center">51.21</td></tr><tr><td align="left" rowspan="2">Penicillin</td><td align="center">189.31</td><td align="center">210.52</td><td align="center">224.82</td><td align="center"><span style="width: 46.612499px;"><svg height="11.275" id="M53" style="vertical-align:-0.20474pt" version="1.1" viewbox="0 0 46.612499 11.275" width="46.612499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center">—</td></tr><tr><td align="center">224.82</td><td align="center">226.63</td><td align="center">250.00</td><td align="center">226.63</td><td align="center"> </td></tr><tr><td align="left">Penicillin/alginate/OSA starch beads</td><td align="center">—</td><td align="center">—</td><td align="center">—</td><td align="center">—</td><td align="center">80.51</td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Peak temperatures and enthalpy changes in the DSC thermograms collected from alginate, OSA starch, unloaded alginate/OSA starch beads, PenG, and PenG-alginate-OSA starch beads.

BioMed Research International

tab2

Table 2

Table 2: Characterization of Antibiotic-Loaded Alginate-Osa Starch Microbeads Produced by Ionotropic Pregelation 