Improvement of Daptomycin Production in Streptomyces roseosporus through the Acquisition of Pleuromutilin Resistance
Figure 3
Kanamycin resistance level among S. roseosporus and its derivatives. (1) ploxp, a strain containing a reporter system in which pdptE was inserted in front of neo; (2) PL11, were derivatives of ploxp with rplC mutation; (3) LDR, derivatives of ploxp-harboring uncharacterized mutation site. (a) Without kanamycin; (b) 400 μg mL−1 kanamycin.
