Research Article

Protective Effect of 3,4-Methylenedioxyphenol (Sesamol) on Stress-Related Mucosal Disease in Rats

Figure 1

Effect of sesamol on water immersion restraint- (WIR-) induced gastric mucosal damage. Rats were divided into five groups of five: Group I, non-WIR (normal) group; Group II, WIR (control) group rats were subjected to WIR; and Groups III–V, sesamol-plus-WIR group rats were orally given sesamol (0.1, 0.3, and 1 mg/kg, resp.) 30 min before WIR. Gastric ulcer index (a) and hemorrhage (b) were assessed after WIR. Data are means ± SD. Significant differences between measurement traits were analyzed using one-way ANOVA. Different letters between groups indicate statistically significant differences ( ).
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(a)
481827.fig.001b
(b)