Research Article

Investigating Mechanisms of Alkalinization for Reducing Primary Breast Tumor Invasion

Figure 7

Effect of sodium bicarbonate on CAIX expression-related fluorescence. (a) Tumor bearing mice ( ) received 84 mg of sodium bicarbonate or PBS p.o. immediately after pretreatment imaging. Subsequent images were acquired at 30 minutes, 1, 3, and 6 hours. CAIX expression is expressed as a percentage of the fluorescence taken prior to treatment. (b) Representative image of experiment comparing PBS-treated mouse to sodium bicarbonate-treated mouse.
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