Figure 7: Effect of sodium bicarbonate on CAIX expression-related fluorescence. (a) Tumor bearing mice ( ) received 84 mg of sodium bicarbonate or PBS p.o. immediately after pretreatment imaging. Subsequent images were acquired at 30 minutes, 1, 3, and 6 hours. CAIX expression is expressed as a percentage of the fluorescence taken prior to treatment. (b) Representative image of experiment comparing PBS-treated mouse to sodium bicarbonate-treated mouse.