The Anti-Arthritic and Immune-Modulatory Effects of NHAG: A Novel Glucosamine Analogue in Adjuvant-Induced Arthritis

<table>The plasma level of NO determined in the normal and arthritic groups. The arthritic control rats showed a significant increase in the levels of nitric oxide (*<svg height="11.375" id="M62" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) compared to the normal control group. The indomethacin and NHAG treatments in arthritic rats showed a significant reduction in the levels of nitric oxide (<sup><i>δ</i></sup><svg height="11.375" id="M63" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.875 11.375" width="66.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> and <sup>‡</sup><svg height="11.375" id="M64" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) compared to the arthritic control group, respectively. Within the treatment groups, no significant difference was found.</table>

BioMed Research International

fig6

Figure 6

Figure 6: The Anti-Arthritic and Immune-Modulatory Effects of NHAG: A Novel Glucosamine Analogue in Adjuvant-Induced Arthritis 