Sabiporide Reduces Ischemia-Induced Arrhythmias and Myocardial Infarction and Attenuates ERK Phosphorylation and iNOS Induction in Rats
Figure 1
(A) Sample tracing EKG data from rats at baseline and myocardial ischemia (MI). (a) ventricular premature beats; (b) Ventricular tachycardia (VT); (c) ventricular fibrillation (VF) (reversible, animal survived); (d) ventricular fibrillation (irreversible, animal died). (B) Dose-dependent effects of sabiporide on (a) ventricular premature beats, (b) ventricular tachycardia duration, and (c) ventricular fibrillation incidence in anesthetized rats. All values are the , . versus the vehicle control group.
