Systems Approaches to Modeling Chronic Mucosal Inflammation

Table 2

Conceptual representation of combinatorial simulations of translational delays of TRAF1 and NF-κB2.

Time-delay combinations (min)	NF-κB2/p100 processing kinetics
(1) TRAF1 (<120) + P100 (<90)	Fast
(2) TRAF1 (≤120) + P100 (=90); OR; TRAF1 (=120) + P100 (≤90)	Near nominal; or; nominal
(3) TRAF1 (≥120) + P100 (>90); OR; TRAF1 (>120) + P100 (≤90); OR; TRAF1 (≤120) + P100 (>90)	Delayed