RNase P-Associated External Guide Sequence Effectively Reduces the Expression of Human CC-Chemokine Receptor 5 and Inhibits the Infection of Human Immunodeficiency Virus 1
Figure 8
Schematic representation of the expression levels of supernatant HIV-1 p24 protein in viral infected cells that did not express an EGS [P(PM1)] or expressed EGS C1 (C1), C2 (C2), and TK1 (TK1). The cells were either infected with X4 strain or R5 strain HIVIIIB. The protein samples were isolated from culture media at 15 days after infection. The levels of p24 protein were measured with an HIV p24 ELISA kit. The values shown are the averages from three independent experiments. Solid bars: ; open bars: HIVIIIB.
