Sympathetic Innervation Induced in Engrafted Engineered Cardiomyocyte Sheets by Glial Cell Line Derived Neurotrophic Factor In Vivo
Figure 3
Neural growth in engrafted engineered cardiomyocyte sheets. (a) Representative images of immunofluorescent staining for -actinin (AA) and growth associated protein 43 (GAP43) in the control and GDNF grafts at 1, 2, and 4 weeks after cardiomyocyte sheets transplantation. Arrows indicate growing nerves in the grafts. (b) Quantitative analysis of GAP43 positive nerve area in the control and GDNF cardiomyocyte sheet grafts (, versus control, ). Scale bars indicate 200 μm. AA: -actinin; GAP43: growth associated protein 43.
