Suitability of Cell-Based Label-Free Detection for Cytotoxicity Screening of Carbon Nanotubes
Table 1
Characterization of CNTs suspended in DMEM + 10% FBS by Dynamic Light Scattering and Laser Doppler Velocimetry (DLS/LDV) and transmission electron microscopy (TEM).
Sample
DLS/LDV data
TEM data
CNT
Hydrodynamic size (nm)
ζ (mV)
Diameter of single CNTs (nm)
Length of single CNTs (nm)
Diameter of CNT bundles (nm)
Length of CNT bundles (nm)
SCNT
16.4
−9.72
~2 nm
n.a.
28.3 ± 10.6
543 ± 60.8
SCNTc
15.7
−8.1
~2 nm
n.a.
62.5 ± 41.9
816 ± 275.4
MCNT8
26.8
−6.96
4.7 ± 0.48
222 ± 126.2
n.a.
n.a.
MCNT8c
16.3
−9.64
4.2 ± 0.8
217 ± 117.9
24.3 ± 5.1
600 ± 282.8*
MCNT20
124.4
−9.78
18.9 ± 0.9
446 ± 77.9
n.a.
n.a.
MCNT20c
38.8
−10.3
15.3 ± 2.5
251 ± 94.4
n.a.
n.a.
MCNT50
51.9
−7.28
62.8 ± 5.7
355 ± 96.4
n.a.
n.a.
MCNT50c
50.4
−11.0
63.6 ± 11.3
392 ± 195.3
n.a.
n.a.
n.a.: not analysed.
*Fraction in bundles approx. 50%.
