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BioMed Research International
Volume 2013 (2013), Article ID 574310, 7 pages
Research Article

Tuning Aerosol Particle Size Distribution of Metered Dose Inhalers Using Cosolvents and Surfactants

1School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK
2Division of Pharmaceutics, College of Pharmacy, University of Texas at Austin, Austin, TX 78712-1113, USA

Received 26 March 2013; Accepted 2 July 2013

Academic Editor: Christine Dufès

Copyright © 2013 Imran Y. Saleem and Hugh D. C. Smyth. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Alessandro Saadat, Bing Zhu, Mehra Haghi, Gregory King, Gaia Colombo, Paul M. Young, and Daniela Traini, “The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler,” Journal of Pharmacy and Pharmacology, 2013. View at Publisher · View at Google Scholar
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  • John Gar Yan Chan, Jennifer Wong, Qi Tony Zhou, Sharon Shui Yee Leung, and Hak-Kim Chan, “Advances in Device and Formulation Technologies for Pulmonary Drug Delivery,” AAPS PharmSciTech, 2014. View at Publisher · View at Google Scholar
  • James W Ivey, Reinhard Vehring, and Warren H Finlay, “Understanding pressurized metered dose inhaler performance,” Expert Opinion on Drug Delivery, pp. 1–16, 2014. View at Publisher · View at Google Scholar
  • Feifei Yang, Xiaobin Liu, Wei Wang, Chunyu Liu, Lihui Quan, and Yonghong Liao, “The effects of surface morphology on the aerosol performance of spray-dried particles within HFA 134a based metered dose formulations,” Asian Journal of Pharmaceutical Sciences, 2015. View at Publisher · View at Google Scholar
  • Yu Pu, Lukeysha C. Kline, Nazia Khawaja, Melissa Van Liew, and Julianne Berry, “Comparison of optical particle sizing and cascade impaction for measuring the particle size of a suspension metered dose inhaler,” Drug Development And Industrial Pharmacy, vol. 41, no. 5, pp. 737–743, 2015. View at Publisher · View at Google Scholar
  • Elsa Bodier-Montagutelli, Eric Morello, Guillaume L’Hostis, Antoine Guillon, Emilie Dalloneau, Renaud Respaud, Nikita Pallaoro, Hélène Blois, Laurent Vecellio, Jérôme Gabard, and Nathalie Heuzé-Vourc’h, “Inhaled phage therapy: a promising and challenging approach to treat bacterial respiratory infections,” Expert Opinion on Drug Delivery, pp. 1–14, 2016. View at Publisher · View at Google Scholar
  • Poonam Sheth, Dennis Sandell, Denise S. Conti, Jay T. Holt, Anthony J. Hickey, and Bhawana Saluja, “Influence of Formulation Factors on the Aerosol Performance of Suspension and Solution Metered Dose Inhalers: A Systematic Approach,” The AAPS Journal, 2017. View at Publisher · View at Google Scholar
  • Rodrigo S. Heyder, Qian Zhong, Reinaldo C. Bazito, and Sandro R.P. da Rocha, “Cellular internalization and transport of biodegradable polyester dendrimers on a model of the pulmonary epithelium and their formulation in pressurized metered-dose inhalers,” International Journal of Pharmaceutics, vol. 520, no. 1-2, pp. 181–194, 2017. View at Publisher · View at Google Scholar