Tuning Aerosol Particle Size Distribution of Metered Dose Inhalers Using Cosolvents and Surfactants
Figure 1
Comparison of HFA 227 formulations with varying concentrations of Pluronic L81 in terms of drug deposited in USP throat of NGI maintaining constant concentration of fluorescein Na and ethanol (data represent mean ± SD, ). * (ANOVA/Tukey’s) 5.45% w/w Pluronic L81 versus 1.22 & 0% w/w Pluronic L81.
