Association of Apolipoprotein A5 Gene −1131T>C Polymorphism with the Risk of Metabolic Syndrome in Korean Subjects

Table 4

Odds ratio of MS according to carriers of the minor allele of the APOA5 −1131T>C polymorphism.

	Subjects	MAF	TT/TC/CC	OR (95% CI)	𝑃 value
Total (2901)	MS	0.336	452/429/123	1.322 (1.165, 1.501)	𝟏.𝟒𝟖𝐄−𝟎𝟓
	Control	0.285	952/808/137	—
Male (1040)	MS	0.352	151/154/47	1.285 (1.050, 1.574)	0.015
	Control	0.307	323/308/57	—
Female (1861)	MS	0.327	301/275/76	1.339 (1.138, 1.576)	𝟒.𝟓𝟐𝐄−𝟎𝟒
	Control	0.273	629/500/80	—

Abbreviations: MS: metabolic syndrome; MAF: minor allele frequency; OR: odds ratio; CI: confidence interval.
Subjects: MS: subjects with ≥3 MS risk factors; control: subjects with <3 MS risk factors.
𝑃 value: adjusted for age and/or sex in multiple logistic regression analysis in an additive model.
Bold indicates statistical significance (𝑃<0.05).