BioMed Research International / 2013 / Article / Tab 1

Clinical Study

Long-Term Effects of Nilvadipine against Progression of the Central Visual Field Defect in Retinitis Pigmentosa: An Extended Study

Table 1

Background clinical data for patients in the treated and control groups.

Treated groupControl groupStatistical significance

Number of patients1922
Gender (M/F)9/1010/12
Age, years at enrollment 0.583
Median (range), years52 (28–72)49 (22–73)0.168
Age, years at initial symptom or diagnosis 0.105
Median (range), years45 (10–66)26 (6–72)0.019*
Observation period, months 0.324
Median (range), months78 (30–120)78 (36–120)0.087
Initial MD value, R, dB 0.896
Median (range), dB−16.81 (−32.22~+0.69)−17.88 (−29.92~−7.83)0.647
Initial MD value, L, dB 0.834
Median (range), dB−15.90 (−33.44~+0.24)−16.57 (−27.72~−4.50)0.647
Correlation between R and L0.960.82<0.001 (T, C)**
Initial sensitivity in CENT4, R, dB 24.57 ± 6.020.935
Median (range), dB24.75 (11.75–36.75)23.75 (13.00–34.75)0.342
Initial sensitivity in CENT4, L, dB 23.40 ± 7.650.616
Median (range), dB24.25 (14.25–36.75)21.50 (12.00–34.75)0.342
Correlation between R and L0.800.63<0.001 (T)** 
0.002 (C)**

Data are expressed as means ± standard deviation.
M: male; F: female; R: right eye; L: left eye; T: treated group; C: control group.
Significance: ; .

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