Figure 2: A 57-year-old woman for mammographic screening. (a) Digital mammogram showed a cluster of amorphous microcalcification (arrow) at the subareolar region of right breast, which was proved to be benign in nature by needle biopsy. The initial BIRADS score was rated as 0 by one reader and 4A by two readers. (b) Tomosynthesis revealed a focal asymmetric density around 7 mm in diameter (arrow), which was rated as BIRADS 4B by two readers and 5 by one reader. The lesion was later proved pathologically to be invasive cancer (T1cN0M0).