Clinical Study

Microscopic Evaluation, Molecular Identification, Antifungal Susceptibility, and Clinical Outcomes in Fusarium, Aspergillus and, Dematiaceous Keratitis

Table 1

Epidemiologic characteristics, risk factors, and clinical features.

VariableFusarium spp. ( )Aspergillus spp. ( )Dematiaceous isolates ( )

Age (in years)41.8452.4646.5
Gender ratio (male : female)2.7121.4
Risk factors
 Trauma other than vegetative body1 (3.8%)4 (26.6%)0
 Trauma with vegetative body11 (42.3%)*04 (33.3%)
 Prior ocular surgery/infection1 (3.8%)5 (33.3%)1 (8.3%)
Seasonal distribution
 Summer6 (23%)3 (20%)1 (8.3%)
 Monson4 (15.3%)7 (46.6%)3 (25%)
 Winter14 (53.8%)7 (46.6%)6 (50%)
Clinical features
 Central location 23 (88.4%)12 (80%)11 (91.6%)
 Size (>10 mm)16 (61.5%)9 (60%)11 (91.6%)
 Hypopyon10 (38.4%)5 (33.3%)9 (75%)*
 Elevated slough19 (73.0%)6 (40%)10 (83.3%)
 Dry texture20 (76.9%)7 (46.6%)9 (75%)
 Serrated ulcer margins21 (80.7%)9 (60%)8 (66.6%)
 Pigmentation0 1 (6.6%)5 (41.6%)
 Endothelial plaque4 (15.3%)0 0
 Dendritic lesions02 (13.3%)0
 Satellite lesions15 (57.6%)8 (53.3%)3 (25%)
 Mean number of days for complete healing57.4*114.8125.6

Group significantly higher compared to other.