Clinical Study
Microscopic Evaluation, Molecular Identification, Antifungal Susceptibility, and Clinical Outcomes in Fusarium, Aspergillus and, Dematiaceous Keratitis
Table 1
Epidemiologic characteristics, risk factors, and clinical features.
| Variable | Fusarium spp. () | Aspergillus spp. () | Dematiaceous isolates () |
| Age (in years) | 41.84 | 52.46 | 46.5 | Gender ratio (male : female) | 2.71 | 2 | 1.4 | Risk factors | | | | Trauma other than vegetative body | 1 (3.8%) | 4 (26.6%) | 0 | Trauma with vegetative body | 11 (42.3%)* | 0 | 4 (33.3%) | Prior ocular surgery/infection | 1 (3.8%) | 5 (33.3%) | 1 (8.3%) | Seasonal distribution | | | | Summer | 6 (23%) | 3 (20%) | 1 (8.3%) | Monson | 4 (15.3%) | 7 (46.6%) | 3 (25%) | Winter | 14 (53.8%) | 7 (46.6%) | 6 (50%) | Clinical features | | | | Central location | 23 (88.4%) | 12 (80%) | 11 (91.6%) | Size (>10 mm) | 16 (61.5%) | 9 (60%) | 11 (91.6%) | Hypopyon | 10 (38.4%) | 5 (33.3%) | 9 (75%)* | Elevated slough | 19 (73.0%) | 6 (40%) | 10 (83.3%) | Dry texture | 20 (76.9%) | 7 (46.6%) | 9 (75%) | Serrated ulcer margins | 21 (80.7%) | 9 (60%) | 8 (66.6%) | Pigmentation | 0 | 1 (6.6%) | 5 (41.6%) | Endothelial plaque | 4 (15.3%) | 0 | 0 | Dendritic lesions | 0 | 2 (13.3%) | 0 | Satellite lesions | 15 (57.6%) | 8 (53.3%) | 3 (25%) | Mean number of days for complete healing | 57.4* | 114.8 | 125.6 |
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Group significantly higher compared to other.
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