Figure 3: Hematoxylin and eosin (HE) stained skin sections ((a)–(d)) of tissues from the healed area of the wound of animals from different groups treated with extract and fractions from S. amaranthoides at 10x magnification. (a) Ulcer in the skin section of rat treated with methanol extract of S. amaranthoides showing moderate amount of grade II granulation tissue beneath the blood clot and fibrin clot. (b) Minimal amount of vascular granulation tissue of grade I in the skin section treated with flavonoid fraction of S. amaranthoides. (c) Complete reepithelisation with no ulceration in vehicle control group. (d) Vascular granulation tissue of grade II with proliferating fibroblasts in the rat skin section treated with standard silver sulfadiazine.