Clinical Study

Cerebral Activation during Von Frey Filament Stimulation in Subjects with Endothelin-1-Induced Mechanical Hyperalgesia: A Functional MRI Study

Figure 5

Cerebral activation in response to ET-1-induced provocation of punctate hyperalgesia at the level of the Anterior Cingulate Cortex (a), at the level of the Insula (b), and the Somatosensory Cortex (c). The results of von Frey filament stimulation of the hyperalgesic right arm contrasted with the results from identical stimulations of the left (noninjected) arm.
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(a)
610727.fig.005b
(b)
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(c)