Research Article
Enhanced Transdermal Delivery of Diclofenac Sodium via Conventional Liposomes, Ethosomes, and Transfersomes
Table 1
Composition, particle size, polydispersity index (PDI), zeta potential, and encapsulation efficiency percent (EE%) of prepared vesicles.
| Formulation | Phospholipid (mg/mL) | Cholesterol (mg/mL) | Span 80 (mg/mL) | Particle size (nm) | PDI | Zeta potential (mV) | EE% |
| Liposome | 100 | 30 | — | 152 ± 21.3 | 0.37 | −39.2 ± 3.9 | 42.61 ± 3.62 | Ethosome | 100 | 30 | — | 202 ± 20.6 | 0.34 | −41.2 ± 2.1 | 51.72 ± 4.36 | Transfersome | 100 | 30 | 30 | 145 ± 6.6 | 0.11 | −38.9 ± 4.1 | 46.73 ± 5.21 |
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