Development of Microencapsulation Delivery System for Long-Term Preservation of Probiotics as Biotherapeutics Agent

Table 5

Different probiotic strain, biomaterial, and size of microcapsule encapsulated by extrusion technique.

Probiotic strain	Material	Size of capsule	Reference
Lactobacillus bulgaricus, Streptococcus thermophilus	1.875% alginate	2.5 mm	[148]
Streptococcus lactis  ssp.  diacetylactis; Streptococcus cremoris	1.875% alginate	2.6 mm	[149]
Streptococcus cremoris	1% alginate	—	[150]
Lactococcus lactis  ssp. cremoris	2% alginate + 0.4% chitosan	2 mm	[12, 147]
Lactobacillus plantarum	2% Alginate + 10% skim milk	2 mm	[151]
Lactococcus lactis  ssp. lactis bv. diacetylactis	1.5% alginate	—	[152]
Lactococcus lactis  ssp.  cremoris	2% alginate	—	[153]
Streptococcus thermophilus; Lactobacillus delbrueckii  ssp.; bulgaricus	2% alginate	—	[154]
Lactococcus lactis  ssp. lactis bv. diacetylactis	1.8% alginate		[155]
Lactobacillus acidophilus	0.6% alginate + starch	5 mm	[156]
Bifidobacterium lactis	0.75% gellan gum + 1% xanthan gum	3 mm	[32, 157, 158]
Lactobacillus reuteri	1% xanthan gum + 0.5% gellan gum	—	[24]
Lactococcus lactis	1% alginate, poly-L-lysine	2 mm	[159]
Lactobacillus reuteri	1.5% alginate + 0.1% poly-L-lysine and 0.1% alginate	619 μm	[160]
Lactobacillus  spp.	1.8% alginate	330–450 μm	[161]
Lactococcus lactis  ssp.  cremoris	2% alginate	1.62 mm	[12]
Lactococcus lactis  ssp.  cremoris	2% alginate + 0.17% alginate	1.89 mm	[12]
Saccharomyces boulardii	1.8% alginate + 0.4% chitosan	356 μm	[162]
Lactobacillus reuteri	2% alginate + 2% corn starch	—	[24]
Lactococcus lactis  ssp.  cremoris	2% alginate + 0.05% poly-L-lysine	1.89 mm	[12]
Bifidobacterium bifidum	2% alginate, 1% gellan, 0.86% peptides, 0.2% FOS	—	[163]
Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum, and Bifidobacterium longum	3% alginate, 1% peptides, 3% FOS	—	[164]
Bifidobacterium longum	2–4% alginate	1.03–2.62 mm	[165]
Lactobacillus reuteri, Escherichia coli	3% alginate	—	[24, 166, 167]
Lactobacillus reuteri	1.75% κ-carrageenan + 0.75% locust bean gum	—	[24]
Lactobacillus acidophilus, Bifidobacterium lactis	1.8% alginate + 1% Hi-Maize starch	—	[140, 168]
Bifidobacterium bifidum	3% κ-carrageenan	—	[169]