Association of CILP2 and ACE Gene Polymorphisms with Cardiovascular Risk Factors in Slovak Midlife Women

Table 1

Anthropometrical, biochemical variables and blood pressure in Slovak women by menopausal status.

Parameter	Total	Premenopause	Postmenopause	𝑃^a
	𝑛=341	𝑛=194	𝑛=147
Age (years)*	49.11±5.61	45.78±3.93	53.50±4.33	<0.001
Weight (kg)*	73.30±15.22	71.92±14.92	75.12±15.46	0.786
WC (cm)	85.79±14.24	83.29±14.63	89.08±13.04	0.722
HC (cm)*	104.29±10.76	102.85±10.17	106.19±11.26	0.804
BMI (kg/m^2)^∗	27.42±5.56	26.59±5.42	28.50±5.57	0.307
WHR	0.82±0.08	0.81±0.09	0.84±0.07	0.602
GMT (µkat/L)*	0.42±0.43	0.34±0.30	0.52±0.54	0.022
ALT (µkat/L)*	0.33±0.20	0.29±0.18	0.38±0.22	0.030
UA (µmol/L)	256.00±65.88	243.88±64.09	272.00±64.98	0.075
TC (mmol/L)	5.43±1.03	5.32±0.92	5.58±1.15	0.840
TG (mmol/L)*	1.41±0.85	1.30±0.71	1.55±0.99	0.621
	𝑛=340	𝑛=193	𝑛=147
Bilirubin (µmol/L)*	8.88±4.16	9.01±4.30	8.72±3.98	0.831
Glucose (mmol/L)*	5.01±1.38	4.78±0.69	5.33±1.90	0.103
	𝑛=315	𝑛=180	𝑛=135
HDL-C (mmol/L)	1.56±0.42	1.57±0.43	1.53±0.41	0.141
LDL-C (mmol/L)	3.25±0.95	3.17±0.85	3.37±1.06	0.734
apoA1 (g/L)*	1.71±0.42	1.72±0.51	1.69±0.25	0.522
apoB (g/L)	0.94±0.25	0.92±0.24	0.97±0.27	0.711
apoB-to-apoA1	0.57±0.18	0.55±0.17	0.59±0.20	0.537
TC-to-HDL-C*	3.73±1.14	3.61±1.08	3.88±1.21	0.176
non-HDL-C	3.89±1.06	3.76±0.94	4.07±1.17	0.624
LDL-C-to-HDL-C*	2.26±0.93	2.18±0.88	2.37±1.00	0.171
log(TG-to-HDL-C)	−0.09±0.29	−0.13±0.29	−0.05±0.29	0.239
	𝑛=309	𝑛=186	𝑛=123
sBP (mmHg)*	123±16.94	120±15.55	127±18.22	0.581
dBP (mmHg)*	79±11.32	78±10.16	80±12.72	0.508

WC: waist circumference; HC: hip circumference; BMI: body mass index; WHR: waist-to-hip ratio; GMT: gamma glutamyl transpeptidase, ALT: alanine aminotransferase; UA: uric acid; TC: total cholesterol; TG: triglycerides, HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein; apoA1: apolipoprotein A1; apoB: apolipoprotein B; sBP: systolic blood pressure; dBP: diastolic blood pressure. Values represent mean ± SD. ∗Not normally distributed parameters; aadjusted for age.