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BioMed Research International
Volume 2013, Article ID 634832, 11 pages
Research Article

HyDEn: A Hybrid Steganocryptographic Approach for Data Encryption Using Randomized Error-Correcting DNA Codes

1National Research Council Canada, 100 des Aboiteaux Street, Moncton, NB, Canada E1A 7R1
2Department of Biology, Université de Moncton, Moncton, NB, Canada E1A 3E9
3Department of Computer Science, Université de Moncton, Moncton, NB, Canada E1A 3E9

Received 30 April 2013; Accepted 29 June 2013

Academic Editor: Tai-hoon Kim

Copyright © 2013 Dan Tulpan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper presents a novel hybrid DNA encryption (HyDEn) approach that uses randomized assignments of unique error-correcting DNA Hamming code words for single characters in the extended ASCII set. HyDEn relies on custom-built quaternary codes and a private key used in the randomized assignment of code words and the cyclic permutations applied on the encoded message. Along with its ability to detect and correct errors, HyDEn equals or outperforms existing cryptographic methods and represents a promising in silico DNA steganographic approach.