Figure 2: Effect of NA-2 on serum levels of IL-1β in arthritic and nonarthritic animals. A significant increase (* ) in the levels of serum IL-1β was found in the arthritic control group compared to normal animals. In contrast to the arthritic control group, both the indomethacin and NA-2 treatments were observed to decrease the IL-1β in the serum of the treated animals ( ) which was comparable to that of the normal control group.