Combined Treatment with Low Concentrations of Decitabine and SAHA Causes Cell Death in Leukemic Cell Lines but Not in Normal Peripheral Blood Lymphocytes

Figure 7

Transcription levels of cyclin-dependent kinase inhibitor p21WAF1, tumor suppressor gene TP53, and several apoptosis-related genes in leukemic cell lines treated by 1 μM DAC and/or 1 μM SAHA monitored by qRT-PCR. Error bars represent ±SEM of three measurements. Statistical significance degree of difference between treated samples and the corresponding control: 𝑃<0.05 (*), 𝑃<0.01 (**), and 𝑃<0.001 (***).

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