P-Glycoprotein-Activity Measurements in Multidrug Resistant Cell Lines: Single-Cell versus Single-Well Population Fluorescence Methods

<table>Intermethods comparison of repeatability for increasing PSC833 concentration. Each graph shows the distribution of calcein fluorescence in 10 samples analyzed with both methods. Cell-normalized well fluorescence in microplate reader is expressed as a function of cell fluorescence concentration (FL1-FC) in flow cytometry for increasing concentrations of PSC833. Straight line corresponds to the mean methods fluorescence ratio.</table>

BioMed Research International

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Figure 5

Figure 5: P-Glycoprotein-Activity Measurements in Multidrug Resistant Cell Lines: Single-Cell versus Single-Well Population Fluorescence Methods 