Preventive Inositol Hexaphosphate Extracted from Rice Bran Inhibits Colorectal Cancer through Involvement of Wnt/β-Catenin and COX-2 Pathways
Figure 2
Effect of IP6 on AOM-induced colonic aberrant crypt foci (ACF) in rats. IP6 decreases the number of ACF in all IP6-fed groups relative to the AOM-only group. Each value expressed as mean ± SD (). *Indicates significant difference by Tukey’s test (). Groups are AOM only, AOM + 0.2% (w/v) of IP6, AOM + 0.5% (w/v) of IP6, and AOM + 1% (w/v) of IP6. (AOM = azoxymethane, ACF = aberrant crypt foci, IP6 = inositol hexaphosphate).
