Clinical Study

The Influence of Hemocoagulation Disorders on the Development of Posttraumatic Cerebral Infarction and Outcome in Patients with Moderate or Severe Head Trauma

Table 2

Demographic characteristics and hemocoagulative abnormalities related to development of cerebral infarction within 1 week in patients with moderate or severe head trauma.

Characteristics of patientsNo. of patientsPTCI (%)P value

Gender
 Male15518 (11.61)0.550
 Female 11010 (9.09)
Age (years)
 <20607 (11.67)0.892
 20–40 15015 (10.00)
 >40556 (10.91)
Admission GCS scores
 3–55210 (19.23)0.005b
 6–812115 (12.40)
 9–12923 (3.26)
Platelet count ( /L)
 <100258 (32.00)0.003b
 100–30021019 (9.05)
 >300301 (3.33)
PT (s)
 ≤8305 (16.67)0.034a
 8–1716211 (6.79)
 ≥177312 (16.44)
APTT (s)
 ≤18274 (14.81)0.043a
 18–5017713 (7.34)
 ≥506111 (18.03)
Fibrinogen (g/L)
 <26915 (21.74)0.001b
 2–41619 (5.59)
 >4354 (11.43)
D-dimer (mg/L)
 ≤2872 (2.30)0.001b
 >217826 (14.61)
DIC scores
 <520913 (6.22)0.000b
 ≥55615 (26.79)

PTCI: posttraumatic cerebral infarction; GCS: Glasgow Coma Score; PT: prothrombin time; APTT: activated partial thromboplastin time; DIC: disseminated intravascular coagulation.
a marked statistical significance.
b more marked statistical significance.