The Influence of Hemocoagulation Disorders on the Development of Posttraumatic Cerebral Infarction and Outcome in Patients with Moderate or Severe Head Trauma
Table 2
Demographic characteristics and hemocoagulative abnormalities related to development of cerebral infarction within 1 week in patients with moderate or severe head trauma.
Characteristics of patients
No. of patients
PTCI (%)
P value
Gender
Male
155
18 (11.61)
0.550
Female
110
10 (9.09)
Age (years)
<20
60
7 (11.67)
0.892
20–40
150
15 (10.00)
>40
55
6 (10.91)
Admission GCS scores
3–5
52
10 (19.23)
0.005b
6–8
121
15 (12.40)
9–12
92
3 (3.26)
Platelet count (/L)
<100
25
8 (32.00)
0.003b
100–300
210
19 (9.05)
>300
30
1 (3.33)
PT (s)
≤8
30
5 (16.67)
0.034a
8–17
162
11 (6.79)
≥17
73
12 (16.44)
APTT (s)
≤18
27
4 (14.81)
0.043a
18–50
177
13 (7.34)
≥50
61
11 (18.03)
Fibrinogen (g/L)
<2
69
15 (21.74)
0.001b
2–4
161
9 (5.59)
>4
35
4 (11.43)
D-dimer (mg/L)
≤2
87
2 (2.30)
0.001b
>2
178
26 (14.61)
DIC scores
<5
209
13 (6.22)
0.000b
≥5
56
15 (26.79)
PTCI: posttraumatic cerebral infarction; GCS: Glasgow Coma Score; PT: prothrombin time; APTT: activated partial thromboplastin time; DIC: disseminated intravascular coagulation.
a marked statistical significance.
b more marked statistical significance.