The Influence of Hemocoagulation Disorders on the Development of Posttraumatic Cerebral Infarction and Outcome in Patients with Moderate or Severe Head Trauma

Table 4

Demographic characteristics, hemocoagulative abnormalities, GCS, PTCI, and outcome of 265 patients with moderate or severe head trauma.

Characteristics of patients	𝑛	GOS 3 months after head trauma (%)
		GOS 1	GOS 2	GOS 3	GOS 4	GOS 5
Gender
Male	155	30 (19.35)	5 (3.26)	22 (14.19)	38 (24.52)	60 (38.71)
Female	110	18 (16.36)	3 (2.73)	11 (10.00)	31 (28.18)	47 (42.73)
Age (years)
<20	60	5 (8.33)	2 (3.33)	9 (15.00)	14 (23.33)	30 (50.00)
20–40	150	31 (20.67)	5 (3.33)	18 (12.00)	37 (24.67)	59 (39.33)
>40	55	12 (21.82)	1 (1.82)	6 (10.91)	18 (32.73)	18 (32.73)
Admission GCS scores
3–5	52	13 (25.00)	4 (7.69)	6 (11.54)	19 (36.54)	10 (19.23)
6–8	121	2 (26.45)	3 (2.48)	13 (10.74)	28 (23.14)	45 (37.19)
9–12	92	3 (3.26)	1 (1.09)	14 (15.22)	22 (23.91)	52 (56.52)
Platelet count (×10^9/L)
<100	25	4 (16.00)	2 (8.00)	5 (20.00)	6 (24.00)	8 (32.00)
100–300	210	44 (20.95)	6 (2.86)	24 (11.43)	54 (25.71)	82 (39.05)
>300	30	0 (0.00)	0 (0.00)	4 (13.33)	9 (30.00)	17 (56.67)
PT (s)
≤8	30	1 (3.33)	2 (6.67)	3 (10.00)	13 (43.33)	11 (36.67)
8–17	162	33 (20.37)	2 (1.23)	16 (9.88)	42 (25.93)	69 (42.59)
≥17	73	14 (19.18)	4 (5.48)	14 (19.18)	14 (19.18)	27 (36.99)
APTT (s)
≤18	27	3 (11.11)	2 (7.41)	3 (11.11)	9 (33.33)	10 (37.04)
18–50	177	38 (21.47)	3 (1.69)	25 (14.12)	39 (22.03)	72 (40.68)
≥50	61	7 (11.48)	3 (4.92)	5 (8.20)	21 (34.43)	25 (40.98)
Fibrinogen (g/L)
<2	69	11 (15.94)	3 (4.35)	8 (11.59)	21 (30.43)	26 (37.68)
2–4	161	35 (21.74)	4 (2.48)	21 (13.04)	35 (21.74)	66 (40.99)
>4	35	2 (5.71)	1 (2.86)	4 (11.43)	13 (37.14)	15 (42.86)
D-dimer (mg/L)
≤2	87	5 (5.75)	2 (2.30)	13 (14.94)	26 (29.89)	41 (47.13)
>2	178	43 (24.16)	6 (3.37)	20 (11.24)	43 (24.16)	66 (37.08)
DIC scores
<5	209	26 (12.44)	5 (2.39)	18 (8.61)	58 (27.75)	102 (48.80)
≥5	56	22 (39.29)	3 (5.36)	15 (26.79)	11 (19.64)	5 (8.93)
Combined with PTCI
Yes	28	10 (35.71)	3 (10.71)	5 (17.86)	6 (21.43)	4 (14.29)
No	237	38 (16.03)	5 (2.11)	28 (11.81)	63 (26.58)	103 (43.46)

GOS: Glasgow Outcome Score; GCS: Glasgow Coma Score; PT: prothrombin time; APTT: activated partial thromboplastin time; DIC: disseminated intravascular coagulation; PTCI: posttraumatic cerebral infarction.