Autophagy and Human Parturition: Evaluation of LC3 Expression in Placenta from Spontaneous or Medically Induced Onset of Labor
Figure 2
Localization of LC3, CRF, and HIF-1α by immunofluorescence method. Immunofluorescence method confirms the localization of LC3, CRF, and HIF-1α in villous and extravillous trophoblasts. Cytokeratin 7 was used as a marker of trophoblastic cells. d: decidua; v: villi. ((a) LC3 expression in trophoblastic cells in the decidual layer, original magnification 20x; (b) LC3 expression in villous trophoblast, original magnification 40x; (c) CRF expression in trophoblastic cells in the decidual layer, original magnification 20x; (d) CRF expression in villous trophoblast, original magnification 40x; (e) HIF-1α expression in trophoblastic cells in the decidual layer, original magnification 20x; (f) HIF-1α expression in villous trophoblast, original magnification 40x; (g) CK7 expression in trophoblastic cells in the decidual layer, original magnification 20x; (h) CK7 expression in villous trophoblast, original magnification 40x.) Images obtained from SP case.
