Hyaluronic Acid Derived from Other Streptococci Supports Streptococcus pneumoniae In Vitro Biofilm Formation

Table 2

Relative quantification of gene expression of Streptococcus pneumoniae planktonic cells by quantitative real-time RT-PCR.

Genes	Encoding proteins	Fold change in HA medium	P value	Fold changes in Glu medium	P value
lytA	N-acetylmuramoyl-L-alanine amidase	0.5	0.04	2.0	0.02
comA	Competence factor transporting ATP-binding/permease protein ComA	0.5	0.03	1.5	0.02
luxS	S-ribosylhomocysteinase	2.1	0.04	1.5	0.04
nanA	Neuraminidase A	3.2	0.04	1.7	0.01
nanB	Neuraminidase B	3.0	0.02	1.2	0.01
bgaA	β-Galactosidase precursor	2.9	0.04	1.5	0.04
strH	N-acetylglucosaminidase	2.1	0.02	1.6	0.04
hysA	Hyaluronidase/hyase	2.1	0.02	1.1	0.02
ugl	Unsaturated glucuronyl hydrolase	2.9	0.02	1.7	0.04
PTS-EIIA	PTS system, N-acetylgalactosamine-specific IIA component	4.0	0.04	3.0	0.03