Research Article

Overexpression of RKIP Inhibits Cell Invasion in Glioma Cell Lines through Upregulation of miR-98

Figure 6

Effects of RKIP on the proliferation and invasion of U251 and U87 cell lines. U251 or U87 cell line was transfected with vector control and RKIP ORF clone. (a) BrdU cell proliferation assay. Ectopic overexpression of RKIP had no effect on proliferation of U251 or U87 cell line, compared to vector ((b), (c)) Transwell assay; upregulated RKIP expression significantly inhibited the invasion ability of U251 and U87 cell lines. The figure is representative of three experiments with similar results.
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