Research Article

N-Acetylcysteine Prevents Hypertension via Regulation of the ADMA-DDAH Pathway in Young Spontaneously Hypertensive Rats

Table 2

Plasma and tissue levels of L-arginine, ADMA, and arginine-to-ADMA ratio.

WKY SHR SHR + NAC

Plasma (μmole/L)
 L-arginine
 ADMA
 Arginine-to-ADMA ratio
Kidney (μmole/L/mg protein)
 L-arginine
 ADMA
 Arginine-to-ADMA ratio

SHR + NAC, spontaneously hypertensive rat treated with N-acetylcysteine; per group; SHR versus WKY; SHR + NAC versus SHR; SHR + NAC versus WKY.