iEzy-Drug: A Web Server for Identifying the Interaction between Enzymes and Drugs in Cellular Networking

Table 1

The jackknife success rates obtained with iEzy-Drug in identifying interactive enzyme-drug pairs and noninteractive enzyme-drug pairs for the benchmark dataset 𝕊 (cf. Online Supporting Information S1).

Method	Acc	Sn	Sp	MCC
iEzy-Drug^a	7425/8157=91.03%	2469/2719=90.81%	4956/5438=91.14%	80.39%
NN predictor^b	85.48%	N/A	N/A	N/A

aSee (27) where the parameters 𝐾=6 and 𝜑=1.5.
^bSee [110].