Embryotoxic and Teratogenic Effects of Nickel in Swiss Albino Mice during Organogenetic Period
Table 2
Influence of Ni+2 (as NiCl2·6H2O) on embryonic developmental of mice.
Parameters
Group I (control)
Group II (46.125 mg Ni/kg b.wt.)
Group III (92.25 mg Ni/kg b.wt.)
Group IV (184.5 mg Ni/kg b.wt.)
Average number of implant sites/dam (I)
Average number of live fetuses/dam (II)
Resorbed embryos (%)
—
4.16
9.09
23.52
Dead fetuses (%)
—
—
—
5.88
Dead macerated fetuses (%)
—
—
—
5.88
Postimplantation death (%)
—
4.16
9.09
35.29
Sex ratio (M : F)
54.16 : 45.83
52.63 : 47.36
50.00 : 50.00
52.94 : 47.05
Fetal weight (gm) (III)
Placental weight (gm) (IV)
(I) and (II) analyzed by one way Mann Whitney -test. (III) and (IV) analyzed by one way analysis of variance.
*Almost significant ().
**Significant ().