Research Article
Embryotoxic and Teratogenic Effects of Nickel in Swiss Albino Mice during Organogenetic Period
Table 3
Fetuses with different anomalies after maternal exposure to Ni+2 (as NiCl2·6H2O).
| | Parameters (%) | Group I
(control) |
Group II
(46.125 mg Ni/kg b.wt.) |
Group III
(92.25 mg Ni/kg b.wt.) | Group IV
(184.5 mg Ni/kg b.wt.) |
| | Hydrocephaly | 0 | 0 | 5.00 | 12.50 | | Microcephaly | 0 | 0 | 5.00 | 0 | | Open eyelids | 0 | 0 | 10.00 | 12.50 | | Microphthalmia | 0 | 5.00 | 5.00 | 6.25 | | Exophthalmia | 0 | 0 | 5.00 | 0 | | Anophthalmia | 0 | 0 | 0 | 0 | | Club foot | 0 | 0 | 0 | 6.25 | | Umbilical hernia | 0 | 0 | 5.00 | 6.25 |
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