A Polyethylenimine-Linoleic Acid Conjugate for Antisense Oligonucleotide Delivery
Figure 5
Effect of N/P ratio on cellular uptake of ODN complexes. (a) Cellular uptake of PEI-LA/Cy3-LOR-2501. (b) Cellular uptake of PEI-LA/ASO and of PEI/ASO. A series of PEI or PEI-LA/LOR-2501 complexes were prepared at varying N/P ratios. Cellular uptake was determined by mean fluorescence intensity by flow cytometry.
