Hsa-miR-15a and Hsa-miR-16-1 Expression Is Not Related to Proliferation Centers Abundance and Other Prognostic Factors in Chronic Lymphocytic Leukemia

Figure 2

The box plots show the distribution of2^−ΔΔCtvalues for each miRNA in all the conditions (cases with or without 13q deletion, hyperplasia). On the𝑦-axis, gene expression quantification values are reported. In the box plots horizontal bars represent median expression values, central rectangles span interquartile range, and dots constitute outlier values. Differences among mean values were calculated by 𝑡-test. The quantification of miRNAs (hsa-miR-16-5p, hsa-miR-15a-5p, hsa-miR-15a-3p, and hsa-miR-16-1-3p) is not tightly associated with the presence of 13q deletion.

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