CXCR1/CXCR2 Antagonism Is Effective in Pulmonary Defense against Klebsiella pneumoniae Infection
Figure 4
Impact of G31P, dexamethasone, or ceftazidime treatments on inflammatory pathology in guinea pigs with Klebsiella pneumoniae. In the G31P-treated group, PMN decreased significantly in BALF compared with the hormones, or antibiotics-treated group (*indicates ). The data show that G31P, hormones, and antibiotics groups have a significant effect in the inhibition of MPO release from lung tissue (*indicates ). G31P decreased significantly the release of MPO in lung tissue compared with the antibiotics group (*indicates ). But there was no significant difference between the G31P and DXM groups.
